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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA064495.25 | 25 µl | - |
7 - 10 business days* |
330.00€
|
|||
| ATA-HPA064495.100 | 100 µl | - |
7 - 10 business days* |
463.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Protein-lysine N-methyltransferase that monomethylates both histones and... more
Product information "Anti-KMT5A"
Protein function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. Plays a negative role in TGF- beta response regulation and a positive role in cell migration. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 90% and to rat: 88%
| Keywords: | Anti-PRSET7, Anti-PR-Set7, Anti-PR/SET07, Anti-H4-K20-HMTase KMT5A, Anti-Lysine-specific methylase 5A, Anti-Lysine N-methyltransferase 5A, Anti-SET domain-containing protein 8, Anti-N-lysine methyltransferase KMT5A |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA064495 |
Properties
| Application: | ICC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KDARKGPLVP FPNQKSEAAE PPKTPPSSCD STNAAIAKQA LKKPIKGKQA PRKKAQGKTQ QNRKLTDFYP VRRSSRKSKA ELQSEERKRI DELIESGK (ATA-APrEST92461) |
Database Information
| KEGG ID : | K11428 | Matching products |
| UniProt ID : | Q9NQR1 | Matching products |
| Gene ID : | GeneID 387893 | Matching products |
| Protein Atlas Nr. : | ENSG00000183955 |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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