37 products were found matching "K11428"!

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UNC0379
UNC0379

Item number: Cay16400-5

SET domain-containing protein 8 (SET8) is a methyltransferase that selectively mono-methylates histone H4 at lysine residue 20, an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor. UNC0379...
Keywords: 6,7-dimethoxy-2-(1-pyrrolidinyl)-N-[5-(1-pyrrolidinyl)pentyl]-4-quinazolinamine
Application: SET8 inhibitor
CAS 1620401-82-2
MW: 413.6 D
From 125.00€ *
Review
Ryuvidine
Ryuvidine

Item number: Cay16614-1

SET domain-containing protein 8 (SETD8) is a methyltransferase that selectively monomethylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor....
Keywords: Cdk4 Inhibitor III, Cyclic-dependent Kinase 4 Inhibitor III, SPS812,...
Application: SETD8 inhibitor
CAS 265312-55-8
MW: 284.3 D
From 44.00€ *
Review
Anti-SETD8
Anti-SETD8

Item number: BPS-25315

SETD8 (UniProtKB/Swiss Prot entry Q9NQR1) is a histone methyl transferase that specifically monomethylates Lys 20 of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression en is enriched during mitosis. SETD8 may also play a role in maintaining silent chromatin by...
Keywords: Anti-PRSET7, Anti-PR-Set7, Anti-PR/SET07, Anti-H4-K20-HMTase KMT5A, Anti-Lysine-specific methylase 5A, Anti-Lysine...
Application: WB
Species reactivity: human
706.00€ *
Review
Set8, active human recombinant protein
Set8, active human recombinant protein

Item number: BPS-51008

Active human SET8 (GenBank Accession No. NM_020382), (amino acids 195-352) with N-terminal GST tag, MW = 44 kDa, expressed in an E. coli expression system.
Keywords: PRSET7, PR-Set7, PR/SET07, H4-K20-HMTase KMT5A, Lysine-specific methylase 5A, Lysine N-methyltransferase 5A, SET...
Application: Enzyme kinetics, inhibitor screening
MW: 44 kD
481.00€ *
Review
SET8 (human recombinant)
SET8 (human recombinant)

Item number: Cay10319-100

Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated. SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and...
Keywords: PRSET7, PR-Set7, PR-Set7, PR/SET07, PR/SET07, H4-K20-HMTase KMT5A, H4-K20-HMTase KMT5A, Lysine-specific methylase 5A,...
Application: Enzyme activity
Expressed in: E.coli
MW: 21.1 kD
537.00€ *
Review
Anti-SETD8
Anti-SETD8

Item number: 100-401-V82

Anti-SETD8 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with SETD8 from species other than human and mouse not tested. Protein function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins....
Keywords: Anti-SETD8, Anti-KMT5A, Anti-PR-Set7, Anti-PR/SET07, EC=2.1.1.-, EC=2.1.1.43, Anti-H4-K20-HMTase SETD8, Anti-Lysine...
Application: WB
Host: Rabbit
Species reactivity: human, mouse
641.00€ *
Review
Anti-SET07, clone 43AT551.86
Anti-SET07, clone 43AT551.86

Item number: NSJ-F40198-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. SET07 is a protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional...
Keywords: Anti-KMT5A, Anti-SETD8, Anti-PR-Set7, Anti-PR/SET07, EC=2.1.1.-, EC=2.1.1.43, Anti-H4-K20-HMTase SETD8, Anti-Lysine...
Application: IHC, IF, WB, ELISA
Host: Mouse
Species reactivity: human, mouse
From 326.00€ *
Review
Anti-SET07, clone 43AT890
Anti-SET07, clone 43AT890

Item number: NSJ-F40199-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. SET07 is a protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional...
Keywords: Anti-KMT5A, Anti-SETD8, Anti-PR-Set7, Anti-PR/SET07, EC=2.1.1.-, EC=2.1.1.43, Anti-H4-K20-HMTase SETD8, Anti-Lysine...
Application: WB, ELISA
Host: Mouse
Species reactivity: human, mouse
From 326.00€ *
Review
Anti-SETD8
Anti-SETD8

Item number: E-AB-61636.120

Protein function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin...
Keywords: Anti-PRSET7, Anti-PR-Set7, Anti-PR/SET07, EC=2.1.1.-, EC=2.1.1.43, Anti-H4-K20-HMTase KMT5A, Anti-Lysine-specific...
Application: WB, IF
Host: Rabbit
Species reactivity: human, mouse, rat
From 198.00€ *
Review
Anti-SETD8
Anti-SETD8

Item number: G-CAB5256.100

Application: IHC, WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 352.00€ *
Review
Anti-KMT5A/SETD8
Anti-KMT5A/SETD8

Item number: G-CAB4136.100

Protein function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin...
Keywords: Anti-PRSET7, Anti-PR-Set7, Anti-PR/SET07, Anti-H4-K20-HMTase KMT5A, Anti-Lysine-specific methylase 5A, Anti-Lysine...
Application: WB
Host: Rabbit
Species reactivity: human, mouse
From 352.00€ *
Review
Anti-SETD8
Anti-SETD8

Item number: G-CAB7305.100

Application: IF, IHC, WB
Host: Rabbit
Species reactivity: human, rat
From 352.00€ *
Review
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