39 products were found matching "K11428"!

SET domain-containing protein 8 (SETD8) is a methyltransferase that selectively monomethylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor....

SET domain-containing protein 8 (SET8) is a methyltransferase that selectively mono-methylates histone H4 at lysine residue 20, an event proven to have an important role in chromatin structure and transcriptional activation. It is also a regulator of p53, mono-methylating lysine 382 of the tumor suppressor. UNC0379...

SETD8 (UniProtKB/Swiss Prot entry Q9NQR1) is a histone methyl transferase that specifically monomethylates Lys 20 of histone H4. This histone modification represents a specific tag for epigenetic transcriptional repression en is enriched during mitosis. SETD8 may also play a role in maintaining silent chromatin by...

Active human SET8 (GenBank Accession No. NM_020382), (amino acids 195-352) with N-terminal GST tag, MW = 44 kDa, expressed in an E. coli expression system.

Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated. SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and...

Anti-SETD8 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. Cross reactivity with SETD8 from species other than human and mouse not tested. Protein function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins....

In 1X PBS, pH 7.4, with 0.09% sodium azide. SET07 is a protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional...

In 1X PBS, pH 7.4, with 0.09% sodium azide. SET07 is a protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional...

Protein function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin...

Description: KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of KMT5A attenuated proliferation and induced apoptosis. Elevated KMT5A expression was...

Description: UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase (SETD8). Target: Histone Methyltransferase. Smiles: COc1cc2nc(nc(NCCCCCN3CCCC3)c2cc1OC)N1CCCC1. References: Ma A, et al. J Med Chem. 2014, 57(15), 6822-6833.

KMT5A Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins (PubMed:12086618, PubMed:12121615, PubMed:15964846, PubMed:17707234, PubMed:27338793). Specifically...