Anti-KLK6

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-15161.20 20 µl -

7 - 16 business days*

71.00€
E-AB-15161.60 60 µl -

7 - 16 business days*

143.00€
E-AB-15161.120 120 µl -

7 - 16 business days*

238.00€
E-AB-15161.200 200 µl -

7 - 16 business days*

396.00€
 
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing... more
Product information "Anti-KLK6"
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. Protein function: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis. [The UniProt Consortium]
Keywords: Anti-KLK6, Anti-Zyme, Anti-SP59, Anti-PRSS18, Anti-Neurosin, Anti-Protease M, EC=3.4.21.-, Anti-Kallikrein-6, Anti-Serine protease 9, Anti-Serine protease 18, KLK6 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-15161

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant protein of human KLK6
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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