Anti-KEAP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-CE1	100 µg		-	-	6 - 10 business days*		848.00€

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Anti-KEAP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-KEAP1"

Anti-KEAP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of KEAP1 are known to exist. Protein function: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome. [The UniProt Consortium]

Keywords:	Anti-INrf2, Anti-KEAP1, Anti-INRF2, Anti-Kelch-like protein 19, Anti-Cytosolic inhibitor of Nrf2, Anti-Kelch-like ECH-associated protein 1
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-CE1

Properties

Application:	ELISA, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	19 amino acid synthetic peptide near the C-terminus of human KEAP1.
Format:	Purified