Anti-KDM1B / LSD2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41836.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for... more

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Product information "Anti-KDM1B / LSD2"

Protein function: Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri- methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys- 36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4. [The UniProt Consortium]

Keywords:	Anti-AOF1, Anti-KDM1B, EC=1.-.-.-, Anti-Lysine-specific histone demethylase 2, Anti-Lysine-specific histone demethylase 1B, Anti-Flavin-containing amine oxidase domain-containing protein 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41836

Properties

Application:	FC, ICC, IF, IP, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide of Human KDM1B / LSD2
MW:	92 kD
Format:	Affinity Purified