Anti-LSD2 (KDM1B)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
BPS-25299	100 µl		-	-	3 - 15 business days*		706.00€

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KDM1B (UniProtKB/Swiss Prot entry Q8NB78), also known as LSD2, is a histone demethylase that... more

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Product information "Anti-LSD2 (KDM1B)"

KDM1B (UniProtKB/Swiss Prot entry Q8NB78), also known as LSD2, is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono and di methylated lysine 4 of histone H3, but has no effect on tri methylated lysine 4, mono , di or tri methylated lysine 9, mono , di or tri methylated lysine 27, mono , di or tri methylated lysine 36 of histone H3, or on mono , di or tri methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.

Keywords:	AOF1, LSD2, C6orf193,
Supplier:	BPS Bioscience
Supplier-Nr:	25299

Properties

Application:	ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Species reactivity:	human
Immunogen:	human KDM1B (lysine (K) specific demethylase 1B) using two KLH conjugated synthetic peptides containing a sequence from the N terminal and the central region of the protein, respectively.
Format:	Serum