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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| NSJ-F54415-0.08ML | 80 µl | - | - |
3 - 10 business days* |
350.00€
|
||
| NSJ-F54415-0.4ML | 400 µl | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. JHDM1D histone demethylase that specifically... more
Product information "Anti-JHDM1D / KDM7A"
In 1X PBS, pH 7.4, with 0.09% sodium azide. JHDM1D histone demethylase that specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3, thereby playing a central role in histone code. This specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. This demethylates H3K9me2 in absence of H3K4me3. Protein function: Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate. [The UniProt Consortium]
| Keywords: | Anti-KDM7A, Anti-JHDM1D, EC=1.14.11.-, Anti-Lysine-specific demethylase 7, Anti-Lysine-specific demethylase 7A, Anti-JmjC domain-containing histone demethylation protein 1D, JHDM1D Antibody / KDM7A |
| Supplier: | NSJ Bioreagents |
| Supplier-Nr: | F54415 |
Properties
| Application: | FC, IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | A portion of amino acids 290-316 from the human protein |
| Format: | Purified |
Database Information
| KEGG ID : | K11445 | Matching products |
| UniProt ID : | Q6ZMT4 | Matching products |
| Gene ID : | GeneID 80853 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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