Anti-JHDM1A

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-475A-T 20 µl (2 blots) -

3 - 9 business days

125.00€
A301-475A-M 100 µl (10 blots) -

3 - 9 business days

290.00€
A301-475A 100 µl (20 µg) -

3 - 9 business days

430.00€
 
Protein function: Histone demethylase that specifically demethylates 'Lys- 36' of histone H3,... more
Product information "Anti-JHDM1A"
Protein function: Histone demethylase that specifically demethylates 'Lys- 36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys- 36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. [The UniProt Consortium]
Keywords: Anti-KDM2A, Anti-CXXC8, EC=1.14.11.27, Anti-F-box protein FBL7, Anti-F-box protein Lilina, Anti-F-box/LRR-repeat protein 11, Anti-Lysine-specific demethylase 2A, Anti-CXXC-type zinc finger protein 8, Anti-[Histone-H3]-lysine-36 demethylase 1A
Supplier: Bethyl Laboratories
Supplier-Nr: A301-475A-T

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Bovine, Dog, Horse, Rabbit, Guinea Pig_10141, Pig, Panda, Orangutan, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Naked Mole Rat, Small-eared Galago, Little Brown Bat, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-475A-T maps to a region between residue 825 and 875 of human JmjC domain-containing histone demethylation protein 1A using the numbering given in entry NP_036440.1 (GeneID 22992).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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