Anti-JAB1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R32297	100 µg		-	-	7 - 12 business days*		790.00€

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0.5mg/ml if reconstituted with 0.2ml sterile DI water. COP9 constitutive photomorphogenic homolog... more

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Product information "Anti-JAB1"

0.5mg/ml if reconstituted with 0.2ml sterile DI water. COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or JAB1, is a gene conserved from humans to Saccharomyces cerevisiae. It is a member of the MOV34 family. COPS5 is mapped to 8q13.1. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. COPS5 can interact with the cytoplasmic domain of the beta-2 subunit of the alpha-L/beta-2 integrin LFA1, and it is the only protein demonstrated to interact with MIF. COPS5, VHL, and TRC8 proteins appear to be linked both physically and functionally, and all 3 may participate in the development of kidney cancer. In addition to that, COPS5 is an essential cofactor for the apoptotic function of E2F1.

Keywords:	Anti-SGN5, Anti-CSN5, Anti-COPS5, EC=3.4.-.-, Anti-Signalosome subunit 5, Anti-COP9 signalosome complex subunit 5, Anti-Jun activation domain-binding protein 1, JAB1 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R32297

Properties

Application:	WB, IHC (paraffin), IF, IP, FC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Amino acids 8-334 of human JAB1 were used as the immunogen for the JAB1 antibody.
Format:	Purified