Anti-ITPR1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-16529.20 20 µl -

7 - 16 business days*

71.00€
E-AB-16529.60 60 µl -

7 - 16 business days*

143.00€
E-AB-16529.120 120 µl -

7 - 16 business days*

238.00€
E-AB-16529.200 200 µl -

7 - 16 business days*

396.00€
 
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by... more
Product information "Anti-ITPR1"
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. Protein function: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways. [The UniProt Consortium]
Keywords: Anti-ITPR1, Anti-IP3R 1, Anti-InsP3R1, Anti-INSP3R1, Anti-Type 1 InsP3 receptor, Anti-IP3 receptor isoform 1, Anti-Inositol 1,4,5-trisphosphate receptor type 1, Anti-Type 1 inositol 1,4,5-trisphosphate receptor, ITPR1 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-16529

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide of human ITPR1
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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