Anti-IP3R1 (ITPR1, inositol 1,4,5-triphosphate receptor, type 1, Inositol 1,4,5-trisphosphate recept

IP3 Receptor 1 is an intracellular channel that when stimulated by inositol 1,4,5-triphosphate mediates the release of calcium from the endoplasmic reticulum. Defects within the gene ITPR1 cause a group of cerebellar disorders known as spinocerebellar ataxia type 15 (SCA15). This receptor is widely expressed in tissue. Applications: Suitable for use in Western Blot and Immunohistochemisty. Other applications not tested. Recommended Dilution: Western Blot: 1:500, Immunohistochemistry (Paraffin): 1:100, Optimal dilutions to be determined by the researcher. Positive Control: C2C12 cell lysates, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.