Anti-ITGB4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R31440	100 µg		-	-	3 - 10 business days*		755.00€

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0.5mg/ml if reconstituted with 0.2ml sterile DI water. ITGB4, also known as CD104, is a receptor... more

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Product information "Anti-ITGB4"

0.5mg/ml if reconstituted with 0.2ml sterile DI water. ITGB4, also known as CD104, is a receptor for the laminin proteins. It tends to associate with alpha 6 subunits and is likely to play a pivotal role in the biology of invasive carcinoma. It was found that ITGB4 was upregulated 6-fold by ZKSCAN3 in transfected human colon cancer cells compared with parental cells and ZKSCAN3 has been confirmed as the promoter of ITGB4 in vitro and in vivo. ITGB4 knockdown by short hairpin RNA countered ZKSCAN3-augmented anchorage-independent colony formation in the colon cancer cell lines. Protein function: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. [The UniProt Consortium]

Keywords:	Anti-ITGB4, Anti-GP150, Anti-CD104, Anti-Integrin beta-4, ITGB4 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R31440

Properties

Application:	WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Human partial recombinant protein (AA 28-266) was used as the immunogen for this ITGB4 antibody.
Format:	Purified