Anti-Integrin alpha-1 (CD49a, CD49 Antigen-like Family Member A, Laminin and Collagen Receptor, VLA-

CD49a is a 200kD type I transmembrane glycoprotein, also known as a1 integrin, VLA-1 a chain, or Integrin a1. It associates with CD29 (B1 integrin) to form VLA-1 complex, a collagen IV and alminin-1 receptor and that is expressed on activated T cells, monocytes, NK cells, smooth muscle cells, neuronal cells, fibroblasts, and mesenchymal cells.CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration and T cell proliferation and cytokine production. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: <0.5ug/10e5 cells in 100ul, Immunohistochemistry: Acetone-fixed, frozen, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.