Anti-Integrin alpha 1 (CD49a, VLA-1, CD49a, Laminin and Collagen Receptor)

Anti-Integrin alpha 1 (CD49a, VLA-1, CD49a, Laminin and Collagen Receptor)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2262-36J.100 100 µg - -

3 - 19 business days*

720.00€
 
Integrin alpha 1 (also VLA-1, CD49a and Laminin and Collagen Receptor) is a 190-210kD member of... more
Product information "Anti-Integrin alpha 1 (CD49a, VLA-1, CD49a, Laminin and Collagen Receptor)"
Integrin alpha 1 (also VLA-1, CD49a and Laminin and Collagen Receptor) is a 190-210kD member of the integrin alpha chain family of molecules. It is found on smooth muscle cells, osteoblasts, adipocytes and intestinal epithelium. Integrin alpha 1 forms a noncovalent heterodimer with Integrin beta 1, and serves as a divalent-cation dependent receptor for collagen types I, IV, VI, XIII and XVI. It also binds the diarrhea-associated NSP4 enterotoxin of rotavirus. Mature human Integrin alpha 1 is a 1151 aa type I transmembrane glycoprotein that contains a 1113aa extracellular domain (ECD) and a 15aa cytoplasmic tail. The ECD contains one vWFA/I-domain (aa147-360) that binds collagen, plus multiple divalent cation binding sites. Potential splice variants exist that show a two and four aa substitution for aa 765-1179. Over aa29-1141 (the ECD), human Integrin alpha 1 shares 88% aa identity with mouse , Integrin alpha 1. , , Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.5-1.0ug/ml, Western Blot: 1.0ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, PBS.. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-ITGA1, Anti-Integrin alpha-1, Anti-Laminin and collagen receptor, Anti-CD49 antigen-like family member A
Supplier: United States Biological
Supplier-Nr: C2262-36J

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Sheep
Reactivity: Human
Immunogen: CHO cell-derived, recombinant human Integrin alpha 1 extracellular domain aa29-1141, P56199.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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