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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
030327.100 | 100 µl | - | - |
3 - 19 business days* |
734.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
IKBKB(Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, also called... more
Product information "Anti-IKBKB"
IKBKB(Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, also called IKK2/IKKB), is a member of the IKK complex which is composed of IKK-alpha, IKK-beta, IKK-gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK-beta has been shown to activate NF-kB and phosphorylate IKB-alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK-beta is essential for activation of IKK by TNF and IL1. Once activated, IKK-beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK-beta activity can also be regulated by MEKK-1. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | 030327 |
Properties
Application: | ELISA, WB |
Antibody Type: | Monoclonal |
Clone: | 13B405 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Purified recombinant fragment of IKBKB expressed in E. coli. |
Purity: | Ascites |
Database Information
KEGG ID : | K07209 | Matching products |
UniProt ID : | O14920 | Matching products |
Gene ID | GeneID 3551 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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