116 products were found matching "K07209"!

1 from 10 pages
No results were found for the filter!
-10 %
Discount Promotion
Mouse IKKB (Inhibitor of kappa B Kinase Beta) ELISA Kit
Mouse IKKB (Inhibitor of kappa B Kinase Beta) ELISA Kit

Item number: ELK-ELK0724.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse IKKB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse IKKB. Next,...
Keywords: IKK2, Ikkb, IkBKB, Ikbkb, IKK-B, NFKBIKB, IKK-beta, I-kappa-B kinase 2, I-kappa-B-kinase beta, Serine/threonine protein...
Application: ELISA
Species reactivity: mouse
365.00€ * From 328.50€ *
Review
BMS 345541 (hydrochloride)
BMS 345541 (hydrochloride)

Item number: Cay16667-1

BMS 345541 is a cell permeable inhibitor of the IkappaB kinases IKKalpha and IKKbeta (IC50s = 4 and 0.3 µM). It is without effect against a panel of other serine/threonine and tyrosine kinases at 100 µM. BMS 345541 inhibits signaling through nuclear factor-kappaB (NF-kappaB) both in cells and in vivo, showing...
Keywords: IKK Inhibitor III, N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine, bis(2,2,2-trifluoroacetate)
Application: Cell permeable IKK-alpha/beta inhibitor
CAS 547757-23-3
MW: 291.8 D
From 60.00€ *
Review
-10 %
COVID-19 Research
Auranofin
Auranofin

Item number: AG-CR1-3611-M025

White to off-white solid. Soluble in DMSO or 100% ethanol. Insoluble in water. Anti-inflammatory and anti-arthritic agent. Represses the activation of the NLRP3/IL-1beta pathway, Inhibitor of 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKbeta subunit 5, Potent thioredoxin...
Keywords: 1-Thio-beta-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetra- acetate, NSC 321521, SKF 39162
Application: Antiinflammatory agent
CAS 34031-32-8
MW: 678,5 D
61.00€ * From 54.90€ *
Review
IKK-16 (hydrochloride)
IKK-16 (hydrochloride)

Item number: Cay13313-5

IKK-16 is a potent inhibitor of IkappaB kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKKalpha, IKKbeta, and IKK complex, respectively, in cell-free assays. It is effective in cells and in animals and has been used delineate the role of NF-kappaB signaling in diverse contexts. IKK-16 has also been...
Keywords: IKK Inhibitor VII, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone,...
Application: IkappaB kinase inhibitor
CAS 1186195-62-9
MW: 520.1 D
From 125.00€ *
Review
BI-605906
BI-605906

Item number: Cay19184-1

BI-605906 is an inhibitor of inhibitor of kappa B kinase subunit beta (IKKbeta, IC50 = 380 nM). It is selective for IKKbeta over insulin-like growth factor 1 (IGF1, IC50 = 7.6 µM) and over 100 kinases in a panel up to 10 µM. BI-605906 partially inhibits IL-1-stimulated activation of IKKepsilon/TBK1 in vitro....
Keywords: 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-thieno[2,3-b]pyridine-2-carboxamide
Application: IKK beta inhibitor
CAS 960293-88-3
MW: 432.5 D
From 102.00€ *
Review
SC-514
SC-514

Item number: Cay10010267-10

SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2) (IC50 = 3-12 µM) that displays greater than 10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK. In synovial fibroblasts stimulated with interleukin (IL)-1beta, SC-514 attenuates NF-kappaB-mediated expression of IL-6,...
Keywords: 4-amino-[2,3'-bithiophene]-5-carboxamide
Application: IKK2 inhibitor
CAS 354812-17-2
MW: 224.3 D
From 60.00€ *
Review
Anti-IKKbeta, clone 10AG2
Anti-IKKbeta, clone 10AG2

Item number: 200-301-H83

Anti-IKKbeta Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with IKKbeta from Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity withAnti-IKKbeta from other sources has not been determined. Protein function: Serine kinase...
Keywords: Anti-IKK2, Anti-IKKB, Anti-IKBKB, Anti-IKK-B, Anti-IkBKB, Anti-NFKBIKB, Anti-IKK-beta, EC=2.7.11.10, Anti-I-kappa-B kinase...
Application: FC, IHC, IP, WB
Host: Mouse
Species reactivity: human, mouse
791.00€ *
Review
IMD 0354
IMD 0354

Item number: Cay17290-1

IMD 0354 is an IKKbeta (IKK2) inhibitor that blocks NF-kappaB phosphorylation (IC50 = ~250 nM) and subsequent NF-kappaB p65 nuclear translocation. It exhibits cardioprotective properties by decreasing expression of P-selectin and ICAM-1 in the vasculature and blocking cardiomyocyte IL-1beta and MCP-1 production,...
Keywords: IKK2 Inhibitor V, N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxy-benzamide
Application: IKK2 inhibitor
CAS 978-62-1
MW: 383.7 D
From 50.00€ *
Review
TPCA-1
TPCA-1

Item number: Cay15115-10

TPCA-1 is a selective inhibitor of IkappaB kinase-2 (IC50s = 17.9 nM and 0.40 µM for IKK2 and IKK1, respectively). Furthermore, it displays greater than 550-fold selectivity over other kinases and enzymes including, p38, MAPK, COX, and JNK. TPCA-1 inhibits the production of LPS-induced TNF-alpha, IL-6, and IL-8 with...
Keywords: IKK2 Inhibitor IV, 2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide
Application: IkappaB kinase-2 inhibitor
CAS 507475-17-4
MW: 279.3 D
From 92.00€ *
Review
ACHP
ACHP

Item number: Cay14504-1

ACHP is an inhibitor of IkappaB kinase beta (IKKbeta) and IKKalpha (IC50s = 8.5 and 250 nM, respectively). It is selective for IKKbeta and IKKalpha over IKKgamma, Syk, and MKK4 (IC50s = >20 µM for all). It reduces the constitutive phosphorylation of IkappaBalpha and NF-kappaB p65 in U266 and NCU-MM-2 multiple...
Keywords: 2-amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile
Application: IKKbeta / IKKalpha inhibitor
CAS 406208-42-2
MW: 364.4 D
From 92.00€ *
Review
Anti-IKK-beta
Anti-IKK-beta

Item number: A301-827A

Protein function: Serine kinase that plays an essential role in the NF- kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of...
Keywords: Anti-IKK2, Anti-IKKB, Anti-IKK-B, Anti-IKBKB, Anti-IkBKB, Anti-NFKBIKB, Anti-IKK-beta, EC=2.7.11.10, Anti-I-kappa-B kinase...
Application: WB, IP
Host: Rabbit
Species reactivity: human
From 164.00€ *
Review
PS-1145
PS-1145

Item number: Cay14862-1

PS-1145 is an IkappaB kinase beta (IKKbeta) inhibitor (IC50 = 88 nM). It selectively inhibits IKKbeta over a panel of 14 kinases (IC50s = >100 nM for all). PS-1145 also inhibits the IKK complex (IC50 = 100 nM). It inhibits the proliferation of MM.1S, U266, and RPMI-8226 myeloma cells when used at concentrations...
Keywords: IKK Inhibitor X, N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide
Application: IKKbeta inhibitor
CAS 431898-65-6
MW: 322.8 D
From 43.00€ *
Review
1 from 10 pages