Anti-IFNAR1 (Anifrolumab Biosimilar Antibody)

Anti-IFNAR1 (Anifrolumab Biosimilar Antibody)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-HDBS0102.100 100 µg - -

9 - 20 business days*

399.00€
 
Protein function: Component of the receptor for type I interferons, including interferons alpha,... more
Product information "Anti-IFNAR1 (Anifrolumab Biosimilar Antibody)"
Protein function: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986, PubMed:32972995). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway. [The UniProt Consortium]
Keywords: Anti-IFNAR, Anti-CRF2-1, Anti-IFNAR1, Anti-IFN-R-1, Anti-IFN-alpha/beta receptor 1, Anti-Type I interferon receptor 1, Anti-Interferon alpha/beta receptor 1, Anti-Cytokine receptor class-II member 1, Anti-Cytokine receptor family 2 member 1
Supplier: Assay Genie
Supplier-Nr: HDBS0102

Properties

Application: ELISA, FC
Antibody Type: Monoclonal
Conjugate: No
Host: Human
Species reactivity: human
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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