Anti-IFNAR1

Anti-IFNAR1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-290A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A304-290A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A304-290A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Component of the receptor for type I interferons, including interferons alpha,... more
Product information "Anti-IFNAR1"
Protein function: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway. [The UniProt Consortium]
Keywords: Anti-IFNAR, Anti-IFNAR1, Anti-CRF2-1, Anti-IFN-R-1, Anti-IFN-alpha/beta receptor 1, Anti-Type I interferon receptor 1, Anti-Interferon alpha/beta receptor 1, Anti-Cytokine receptor family 2 member 1, Anti-Cytokine receptor class-II member 1
Supplier: Bethyl Laboratories
Supplier-Nr: A304-290A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Himalayan Marmot, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A304-290A-T maps to a region between residue 507 to 557 of human Interferon (alpha, beta and omega) Receptor 1 using the numbering given in entry NP_000620.2 (GeneID 3454).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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