Anti-IFNAR1 / Interferon alpha receptor 1, clone AF-9

Anti-IFNAR1 / Interferon alpha receptor 1, clone AF-9
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ4481 100 µg - -

3 - 10 business days*

580.00€
 
Antibody in PBS with 0.02% sodium azide and 50% glycerol. Component of the receptor for type I... more
Product information "Anti-IFNAR1 / Interferon alpha receptor 1, clone AF-9"
Antibody in PBS with 0.02% sodium azide and 50% glycerol. Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity). [UniProt] Protein function: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta- subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway. [The UniProt Consortium]
Keywords: Anti-IFNAR, Anti-CRF2-1, Anti-IFNAR1, Anti-IFN-R-1, Anti-IFN-alpha/beta receptor 1, Anti-Type I interferon receptor 1, Anti-Interferon alpha/beta receptor 1, Anti-Cytokine receptor family 2 member 1, Anti-Cytokine receptor class-II member 1, IFNAR1 Antibo
Supplier: NSJ Bioreagents
Supplier-Nr: RQ4481

Properties

Application: WB
Antibody Type: Monoclonal
Clone: AF-9
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: A synthetic peptide from human Interferon Receptor alpha
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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