Anti-Human IL-13 NALE(TM) Purified (Clone: PVM13-1)

Anti-Human IL-13 NALE(TM) Purified (Clone: PVM13-1)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-43-1038-50 50 µg -

3 - 11 business days*

362.00€
 
The PVM13-1 monoclonal antibody bings to human IL-13. IL-13 is an immunoregulatory cytokine... more
Product information "Anti-Human IL-13 NALE(TM) Purified (Clone: PVM13-1)"
The PVM13-1 monoclonal antibody bings to human IL-13. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1Beta, TNF-Alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. The PVM13-1 antibody is reported to be a neutralizing antibody. Protein function: Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages. [The UniProt Consortium]
Keywords: Anti-IL13, Anti-NC30, Anti-IL-13, Anti-Interleukin-13, Monoclonal Antibody to Human IL-13 NALE(TM) Purified (Clone: PVM13-1)
Supplier: Abeomics
Supplier-Nr: 43-1038

Properties

Application: FA
Antibody Type: Monoclonal
Clone: PVM13-1
Conjugate: No
Host: Mouse
Species reactivity: human
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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