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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-43-1038-50 | 50 µg | - |
3 - 11 business days* |
362.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The PVM13-1 monoclonal antibody bings to human IL-13. IL-13 is an immunoregulatory cytokine... more
Product information "Anti-Human IL-13 NALE(TM) Purified (Clone: PVM13-1)"
The PVM13-1 monoclonal antibody bings to human IL-13. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1Beta, TNF-Alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. The PVM13-1 antibody is reported to be a neutralizing antibody. Protein function: Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages. [The UniProt Consortium]
Keywords: | Anti-IL13, Anti-NC30, Anti-IL-13, Anti-Interleukin-13, Monoclonal Antibody to Human IL-13 NALE(TM) Purified (Clone: PVM13-1) |
Supplier: | Abeomics |
Supplier-Nr: | 43-1038 |
Properties
Application: | FA |
Antibody Type: | Monoclonal |
Clone: | PVM13-1 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Format: | Affinity Purified |
Database Information
KEGG ID : | K05435 | Matching products |
UniProt ID : | P35225 | Matching products |
Gene ID : | GeneID 3596 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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