Anti-HSPE1 (10kD chaperonin, Chaperonin 10)

HSPE1(heat shock 10kDa protein 1 (chaperonin 10)), also called CPN10, GROES, CHAPERONIN 10 , HOMOLOG, cpn10 HOMOLOG or HSP10, is a protein that in humans is encoded by the HSPE1 gene. , GroES is a heptameric ring of identical 10.4-kD subunits that binds to each end of GroEL to form a , symmetric, functional heterodimer. The HSP10 gene consists of 4 exons. The HSPE1 gene is mapped to , 2q33.1. The transcriptional activity of the promoter fragment in the HSP60 direction is approximately , twice that in the HSP10 direction under normal growth conditions, upon heat shock, promoter activity in , either direction increased by a factor of approximately 12. Mutational drifts performed in vitro with 4 , different enzymes indicated the GroES overexpression doubled the number of accumulating mutations, , and promoted the folding of enzyme variants carrying mutations in the protein core and/or mutations with , higher destabilizing effects. UniProt Number: P61604, Gene ID: HSPE1, Applications: Suitable for use in Western Blot, Immunohistochemistry (Paraffin) and Immunocytochemistry. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20?C for one year. After reconstitution, store at 4?C for one month. Can also be aliquoted and stored frozen at -20?C for long term., Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.