Anti-HMGCR, clone CL0260

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-AMAb90619.25	25 µl		-		7 - 10 business days*		330.00€
ATA-AMAb90619.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to... more

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Product information "Anti-HMGCR, clone CL0260"

Protein function: Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis (PubMed:2991281, PubMed:21357570, PubMed:6995544). HMGCR is the main target of statins, a class of cholesterol-lowering drugs (PubMed:11349148, PubMed:18540668). [The UniProt Consortium] Validated by genetic and standard strategies. Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.. Epitope specificity: TLMETHERGVSIRRQ.

Keywords:	Anti-HMG-CoA reductase, Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase
Supplier:	Atlas Antibodies
Supplier-Nr:	AMAb90619

Properties

Application:	WB, IHC
Antibody Type:	Monoclonal
Clone:	CL0260
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GAKFLSDAEI IQLVNAKHIP AYKLETLMET HERGVSIRRQ LLSKKLSEPS SLQYLPYRDY NYSLVMGACC ENVIGYMPIP VGVAGPLCLD EKEFQVPMAT TEGCLVASTN RGCRAIGLGG GASSRVLADG MTRGPVVRLP RACDSAEVKA WLETSEGFAV IKEAFDSTSR FARLQKLHTS IAGRNLYIRF QSRSGDAMGM NMISKGTEKA LSKLHEYFPE MQILAVSGNY CTDKKPAAIN WIEGRGKSVV CEAVIPAKVV REVLKTTT