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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES2536.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES2536.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with... more
Product information "Anti-HLA-DOalpha"
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008], Protein function: Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B- cells. Modifies peptide exchange activity of HLA-DM. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Endosome membrane, Single-pass type I membrane protein. Lysosome membrane, Single-pass type I membrane protein. Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
Keywords: | Anti-HLA-DOA, Anti-HLA-DNA, Anti-MHC DN-alpha, Anti-MHC DZ alpha, Anti-MHC class II antigen DOA, Anti-HLA class II histocompatibility antigen, DO alpha chain, HLA-DOalpha rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES2536 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | The antiserum was produced against synthesized peptide derived from human HLA-DOA. AA range:71-120 |
MW: | 34 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K06752 | Matching products |
UniProt ID : | P06340 | Matching products |
Gene ID | GeneID 3111 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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