Anti-HCAR1 / Hydroxycarboxylic acid receptor 1 / GPR81

In 1X PBS, pH 7.4, with 0.09% sodium azide. HCAR1 is a G-protein coupled receptor that is primarily found in various tissues throughout the body, including the liver, adipose tissue, and skeletal muscle. When activated by its ligand, which in this case is a specific type of hydroxycarboxylic acid, HCAR1 plays a key role in regulating glucose and lipid metabolism. One of the most intriguing aspects of HCAR1 is its ability to promote the use of fats as an energy source, a process known as fatty acid oxidation. By activating HCAR1, the body is able to break down fatty acids more efficiently, leading to improved metabolic health and potentially aiding in weight management. Additionally, HCAR1 has been shown to have anti-inflammatory effects, which can help combat chronic inflammation associated with metabolic disorders such as obesity and diabetes. By modulating the body's immune response, HCAR1 can help reduce inflammation and improve overall health. Protein function: Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway. [The UniProt Consortium]