14 products were found matching "K08401"!

GPR81, also known as hydroxycarboxylic acid receptor 1 (HCAR1), is a recently de-orphanized receptor that is activated by lactic acid (EC50 ~ 1.5 mM) but not by other hydroxycarboxylic acids. 3-chloro-5-hydroxy BA is an agonist of GPR81 (EC50 = 16 µM) that is inactive against the related GPR109a (HCAR2) receptor. It...

Protein function: Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway. [The UniProt Consortium]

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: G protein-coupled receptor 81 Protein function: Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway. [The UniProt Consortium]

Recombinant Human GPR81 Protein with C-terminal human Fc tag. GPR81(Met1-Leu21) hFc(Glu99-Ala330), Protein function: Acts as a receptor for L-lactate and mediates its Anti-lipolytic effect through a G(i)-protein-mediated pathway. [The UniProt Consortium]

Description: 3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 µM). Target: Others, GPCR. Smiles: OC(=O)C1=CC(Cl)=CC(O)=C1. References: Dvorak C A , Liu C , Shelton J , et al. Identification of Hydroxybenzoic Acids as Selective Lactate Receptor (GPR81) Agonists with...

Human HCAR1 (Hydroxycarboxylic acid receptor 1) ELISA Kit is a high quality kit for research use only from Assay Genie. The Human HCAR1 (Hydroxycarboxylic acid receptor 1) ELISA Kit comes in a 96 Assays format and reacts against Human samples. We ship this kit on Gel Pack and kits should be stored at 2-8°C Protein...

In 1X PBS, pH 7.4, with 0.09% sodium azide. HCAR1 is a G-protein coupled receptor that is primarily found in various tissues throughout the body, including the liver, adipose tissue, and skeletal muscle. When activated by its ligand, which in this case is a specific type of hydroxycarboxylic acid, HCAR1 plays a key...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000, Optimal dilutions...

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Northern analyses revealed GPR81 expression in the pituitary. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not...