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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R31967 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. GRP94 (94 kDa glucose-regulated protein),... more
Product information "Anti-GRP94"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. GRP94 (94 kDa glucose-regulated protein), also called Endoplasmin, is a chaperone protein that in humans is encoded by the HSP90B1 gene. This gene encodes a member of a family of adenosine triphosphate (ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. Protein function: Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD) (PubMed:18264092). Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) and secretion, the translocation process is mediated by the cargo receptor TMED10 (PubMed:32272059). [The UniProt Consortium]
Keywords: | Anti-GRP94, Anti-GRP-94, Anti-Endoplasmin, Anti-gp96 homolog, Anti-Tumor rejection antigen 1, Anti-94 kDa glucose-regulated protein, Anti-Heat shock protein 90 kDa beta member 1, GRP94 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R31967 |
Properties
Application: | WB, IHC (paraffin), IF, FC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Amino acids 43-221 of human GRP94 |
Format: | Purified |
Database Information
KEGG ID : | K09487 | Matching products |
UniProt ID : | P14625 | Matching products |
Gene ID | GeneID 7184 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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