Anti-GNRHR, NT (GNRHR, GRHR, Gonadotropin-releasing hormone receptor)

Anti-GNRHR, NT (GNRHR, GRHR, Gonadotropin-releasing hormone receptor)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
036155.200 200 µl - -

3 - 19 business days*

728.00€
 
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a... more
Product information "Anti-GNRHR, NT (GNRHR, GRHR, Gonadotropin-releasing hormone receptor)"
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-GRHR, Anti-GNRHR, Anti-GnRH-R, Anti-GnRH receptor, Anti-Gonadotropin-releasing hormone receptor
Supplier: United States Biological
Supplier-Nr: 036155

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: GNRHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human GNRHR.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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