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The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. Protein function: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF- kappa-B. Required for normal osteoclastogenesis. [The UniProt Consortium]
Keywords:
Anti-GLO1, Anti-Glx I, EC=4.4.1.5, Anti-Glyoxalase I, Anti-Aldoketomutase, Anti-Methylglyoxalase, Anti-Ketone-aldehyde mutase, Anti-Lactoylglutathione lyase, Anti-S-D-lactoylglutathione methylglyoxal lyase, GLO1 Polyclonal Antibody
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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