62 products were found matching "K01759"!
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Anti-GLO1
Item number: ABS-KC-2941.100
Protein function: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis. [The UniProt Consortium]
| Keywords: | Anti-Lactoylglutathione lyase, Anti-Aldoketomutase, Anti-Glyoxalase I, Anti-Glx I, Anti-Ketone-aldehyde mutase,... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Glyoxalase I inhibitor 5
Item number: TGM-T61103-2mg
Description: Glyoxalase I inhibitor 5 (Compound 9h) is a potent glyoxalase I (Glo-I) inhibitor with an IC50 of 1.28 µM, showing potential as an anticancer agent [1]. Target: Others. Smiles: N(=N/C1=CC(S(N)(=O)=O)=C(C)C=C1)\C=2C3=C(C(O)=CC2)N=CC=C3
| Application: | Glyoxalase I (GLO1, lactoylglutathione lyase) inhibitor |
| CAS | 2455508-17-3 |
| MW: | 342.37 D |
98.00€
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Glyoxalase I inhibitor 6
Item number: TGM-T61692-2mg
Description: Glyoxalase I inhibitor 6 (Compound 9j) is an inhibitor of glyoxalase I (Glo-I) with an IC50 of 1.13 µM, exhibiting potential as a low-toxicity anticancer agent [1]. Target: Others. Smiles: N(=N/C1=CC(S(N)(=O)=O)=C(C)C=C1)\C=2C3=C(C(O)=C(C(O)=O)C2)C=CC=C3
| Application: | Glyoxalase I (GLO1, lactoylglutathione lyase) inhibitor |
| CAS | 2455508-19-5 |
| MW: | 385.39 D |
98.00€
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Glyoxalase I inhibitor 2
Item number: TGM-T62699-100mg
Description: Glyoxalase I inhibitor 2 (compound 26) is a potent inhibitor of glyoxalase I (GLO1) with an IC50 of 0.5 µM, and has potential applications in depression and anxiety studies. Target: Others. Smiles: N(S(=O)(=O)C1=CC=CC=N1)C=2C3=C(C=C(CCC4=CC(OC)=CC(OC)=C4)C2)C=CC=N3
| Application: | Glyoxalase I (GLO1, lactoylglutathione lyase) inhibitor |
| CAS | 2314467-61-1 |
| MW: | 449.52 D |
From 1,520.00€
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Lactoylglutathione lyase/GLO1 Protein, Human, Recombinant...
Item number: TGM-TMPH-01601-100ug
Description: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis.
| Keywords: | Aldoketomutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase, GLO1, Lactoylglutathione lyase,... |
| MW: | 47.8 kD |
From 198.00€
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GLO1 Protein, Mouse, Recombinant (His)
Item number: TGM-TMPY-01618-100ug
Description: Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyoxalase I is a ubiquitous cellular defense enzyme involved in the detoxification of...
| Keywords: | AW550643, Glo-1, Glo-1s, Qglo, 1110008E19Rik, 0610009E22Rik, Glo1-s, 2510049H23Rik, Glo1-r, GLY1, glyoxalase I, Glo-1r |
| MW: | 21.6 kD |
699.00€
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Glyoxalase I inhibitor 1
Item number: TGM-T64153-100mg
Description: Glyoxalase I inhibitor 1 is a potent inhibitor of glyoxalase I (GLO1) (IC50: 26 nM). Target: Others. Smiles: N(C1=C(NS(C)(=O)=O)C=CC=C1)C2=NC(NC3=CC=C(C(=O)C4=CC=C(NC(CCCC#C)=O)C=C4)C=C3)=NC=C2F
| Application: | Glyoxalase I (GLO1, lactoylglutathione lyase) inhibitor |
| CAS | 1622952-07-1 |
| MW: | 586.64 D |
From 1,520.00€
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Glyoxalase I inhibitor 4
Item number: TGM-T64023-100mg
Description: Glyoxalase I inhibitor 4 is a potent inhibitor of glyoxalase I (GLO1) (Ki: 10 nM). Target: Others. Smiles: N(C(SC[C@H](NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O)=O)(O)C1=CC=C(I)C=C1
| Application: | Glyoxalase I (GLO1, lactoylglutathione lyase) inhibitor |
| CAS | 250155-72-7 |
| MW: | 568.34 D |
From 2,142.00€
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Glyoxalase I inhibitor 7
Item number: TGM-T61286-100mg
Description: Glyoxalase I inhibitor 7 (Compound 6) is a potent glyoxalase I (Glo-I) inhibitor with an IC50 of 3.65 µM, exhibiting potential as an anticancer agent [1]. Target: Others. Smiles: N(=N/C1=CC(S(N)(=O)=O)=C(C)C=C1)\C=2C3=C(C(N)=CC2)C=CC(O)=C3
| Application: | Glyoxalase I (GLO1, lactoylglutathione lyase) inhibitor |
| CAS | 2455508-31-1 |
| MW: | 356.4 D |
From 1,520.00€
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Glyoxalase I inhibitor 3
Item number: TGM-T61534-100mg
Description: Glyoxalase I Inhibitor 3 (compound 22g), a potent inhibitor of glyoxalase I (GLO1), demonstrates an IC50 of 0.011 µM, indicating significant efficacy. This compound shows promise for research into depression and anxiety [1]. Target: Others. Smiles: ON1C(=CC(=CC1=O)C2=CC=CC=C2)C=3C=C4C(=NC3)N(CCCOC)C=C4
| Application: | Glyoxalase I (GLO1, lactoylglutathione lyase) inhibitor |
| CAS | 1415388-25-8 |
| MW: | 375.42 D |
From 1,520.00€
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Glyoxalase I inhibitor free base
Item number: TGM-T11432-100mg
Description: Glyoxalase I inhibitor (free base), a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor. Target: Others. Smiles: CCOC(=O)CNC(=O)[C@H](CSC(=O)N(O)c1ccc(Br)cc1)NC(=O)CC[C@H](N)C(=O)OCC. References: Bollong MJ, et al. A metabolite-derived protein modification integrates glycolysis...
| Application: | Glyoxalase I (GLO1, lactoylglutathione lyase) inhibitor |
| CAS | 174568-92-4 |
| MW: | 577.45 D |
From 752.00€
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Glyoxalase I inhibitor
Item number: TGM-T11433-100mg
Description: Glyoxalase I inhibitor, a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor. Target: Others. Smiles: Cl.CCOC(=O)CNC(=O)[C@H](CSC(=O)N(O)c1ccc(Br)cc1)NC(=O)CC[C@H](N)C(=O)OCC
| Application: | Glyoxalase I (GLO1, lactoylglutathione lyase) inhibitor |
| CAS | 221174-33-0 |
| MW: | 613.91 D |
From 861.00€
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