Anti-GDF6

Anti-GDF6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with GDF6 from other sources has not been determined. Protein function: Growth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map. Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Plays a key role in establishing boundaries between skeletal elements during development. May signal through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A. [The UniProt Consortium]