Anti-GABRG2

Anti-GABRG2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB1733.20 20 µl -

9 - 20 business days*

149.00€
 
Protein function: Ligand-gated chloride channel which is a component of the heteropentameric... more
Product information "Anti-GABRG2"
Protein function: Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:2538761, PubMed:29950725). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:23909897, PubMed:25489750, PubMed:27864268). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer. The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity (PubMed:23909897, PubMed:25489750). The alpha2/beta2/gamma2 receptor exhibits synatogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity. Functions also as histamine receptor and mediates cellular responses to histamine. [The UniProt Consortium]
Keywords: Anti-GABRG2, Anti-GABA(A) receptor subunit gamma-2, Anti-Gamma-aminobutyric acid receptor subunit gamma-2
Supplier: Assay Genie
Supplier-Nr: CAB1733

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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