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This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein... more
Product information "Anti-FLNB"
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. Protein function: Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro. [The UniProt Consortium]
Keywords: | Anti-Fh1, Anti-FLNB, Anti-FLN1L, Anti-FLN-B, Anti-ABP-278, Anti-Filamin-3, Anti-Filamin-B, Anti-Beta-filamin, Anti-Truncated ABP, Anti-ABP-280 homolog, Anti-Filamin homolog 1, Anti-Thyroid autoantigen, Anti-Actin-binding-like protein, FLNB Polyclonal Anti |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-62747 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human FLNB |
Database Information
KEGG ID : | K04437 | Matching products |
UniProt ID : | O75369 | Matching products |
Gene ID | GeneID 2317 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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