102 products were found matching "K04437"!
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Simufilam
Item number: LKT-S336505.1
Simufilam was first introduced as having the potential to reduce biomarkers of Alzheimer's disease. The original data has since become suspect and could not be found. Fraud charges have been filed by the SEC. Simufilam may or may not have some useful bioactivities. The proper research, with proper data collection...
| Keywords: | PTI-125, PTI-910, C0105, 1,4,8-Triazaspiro(4.5)decan-2-one, 8-methyl-1-(phenylmethyl)-,... |
| Application: | Unlikely to reverse Alzheimer's |
| CAS | 1224591-33-6 |
| MW: | 259.35 D |
From 143.00€
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Simufilam Dihydrochloride
Item number: LKT-S336507.100
Simufilam was first introduced as having the potential to reduce biomarkers of Alzheimer's disease. The original data has since become suspect and could not be found. Fraud charges have been filed by the SEC. Simufilam may or may not have some useful bioactivities. The proper research, with proper data collection...
| Keywords: | PTI-125 dihydrochloride, PTI diHCl, JP8XRG9A58, 4-benzyl-8-methyl-1,4,8-triazaspiro[4.5]decan-3-one,dihydrochloride |
| Application: | Unlikely to reverse Alzheimer's |
| CAS | 2480226-06-8 |
| MW: | 332.3 D |
From 229.00€
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Anti-FLNA
Item number: ABS-KC-2561.100
Protein function: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration...
| Keywords: | Anti-Filamin-A, Anti-FLN-A, Anti-Actin-binding protein 280, Anti-ABP-280, Anti-Alpha-filamin, Anti-Endothelial... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-FLNA
Item number: ABS-KC-3174.100
Protein function: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration...
| Keywords: | Anti-Filamin-A, Anti-FLN-A, Anti-Actin-binding protein 280, Anti-ABP-280, Anti-Alpha-filamin, Anti-Endothelial... |
| Application: | IP |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-FLNA
Item number: ABS-OC-255.100
Protein function: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNB may allow neuroblast migration...
| Keywords: | Anti-Filamin-A, Anti-FLN-A, Anti-Actin-binding protein 280, Anti-ABP-280, Anti-Alpha-filamin, Anti-Endothelial... |
| Host: | Mouse |
| Species reactivity: | human |
From 232.00€
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PTI-125 (hydrochloride)
Item number: Cay41859-10
PTI-125 is a purported binding agent of filamin A, a cytoskeletal protein said to stabilize the interaction between amyloid-beta (1-42) (Abeta42) and the alpha7 nicotinic acetylcholine receptor (nAChR). PTI-125 reportedly binds to filamin A to reverse an aberrant conformational change induced by Abeta42, which...
| Keywords: | 8-methyl-1-(phenylmethyl)-1,4,8-triazaspiro[4.5]decan-2-one, monohydrochloride |
| Application: | Purported Filamin A binding agent |
| CAS | 2480226-06-8 |
| MW: | 332.3 D |
From 226.00€
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simufilamum
Item number: TGM-T9569-100mg
Description: Simufilam (PTI-125) is a low toxicity, orally active filamin A ( FLNA ) activator. Simufilam preferentially binds altered FLNA and restores its native conformation, restores receptor and synaptic activities, reduces its a7nAChR/TLR4 associations and downstream pathologies. Simufilam can be used in...
| Application: | Targets filamin-A (FLNA) |
| CAS | 1224591-33-6 |
| MW: | 259.35 D |
From 1,149.00€
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Filamin-A Protein, Human, Recombinant (His & Myc)
Item number: TGM-TMPH-01342-100ug
Description: Filamin-A Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.0 kDa and the accession number is P21333.
| Keywords: | Filamin-1, FLNA, Alpha-filamin, Actin-binding protein 280, Endothelial actin-binding protein, Filamin-A, Non-muscle filamin |
| MW: | 38.0 kD |
From 281.00€
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Kartogenin
Item number: TGM-T1748-100mg
Description: Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes. Target: TGF-beta/Smad. Smiles: OC(=O)c1ccccc1C(=O)Nc1ccc(cc1)-c1ccccc1. References: Johnson K, et al. Science. 2012, 336(6082), 717-721.
| Keywords: | KGN |
| Application: | Chondrogenesis inducer |
| CAS | 4727-31-5 |
| MW: | 317.34 D |
From 31.00€
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Anti-FLNA
Item number: CSB-PA002535.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-FLN, Anti-FLNA, Anti-FLN-A, Anti-ABP-280, Anti-Filamin-A, Anti-Filamin-1, Anti-Alpha-filamin, Anti-Non-muscle... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 126.00€
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Anti-Phospho-FLNA (S2152)
Item number: CSB-PA000688.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-phospho-FLN, Anti-phospho-FLNA, Anti-phospho-FLN-A, Anti-phospho-ABP-280, Anti-phospho-Filamin-A,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat, monkey |
From 126.00€
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Anti-FLNA
Item number: CSB-PA985162.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: FLNA. Antigen Species: Human
| Keywords: | Anti-FLN, Anti-FLNA, Anti-FLN-A, Anti-ABP-280, Anti-Filamin-A, Anti-Filamin-1, Anti-Alpha-filamin, Anti-Non-muscle... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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