Anti-Filaggrin, clone FLG/1562

Anti-Filaggrin, clone FLG/1562
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3331SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. Filaggrin (FLG) is an intermediate... more
Product information "Anti-Filaggrin, clone FLG/1562"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery. Protein function: Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. [The UniProt Consortium]
Keywords: Anti-FLG, Anti-Filaggrin, Filaggrin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3331SAF-100UG

Properties

Application: FC, IHC, IF
Antibody Type: Monoclonal
Clone: FLG/1562
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.
Format: Purified

Database Information

UniProt ID : P20930 | Find alternatives
Gene ID GeneID 2312 | Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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