Anti-Filaggrin, clone FLG/1561

Anti-Filaggrin, clone FLG/1561
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3330-20UG 20 µg - -

3 - 10 business days

NSJ-V3330-100UG 100 µg - -

3 - 10 business days

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Filaggrin (FLG) is an... more
Product information "Anti-Filaggrin, clone FLG/1561"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery. Protein function: Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. [The UniProt Consortium]
Keywords: Anti-FLG, Anti-Filaggrin, Filaggrin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3330-20UG


Application: FC, IHC, IF
Antibody Type: Monoclonal
Clone: FLG/1561
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.
Format: Purified

Database Information

UniProt ID : P20930 | Find alternatives
Gene ID GeneID 2312 | Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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