Anti-Fibronectin, clone HFN7.1

Anti-Fibronectin, clone HFN7.1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2124-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V2124-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The fibronectin dimer consists of... more
Product information "Anti-Fibronectin, clone HFN7.1"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The fibronectin dimer consists of two disulfide linked monomers of approximately 220 kD, and is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing. Fibronectin accumulates at the site of injury and, along with fibrin, forms a blood clot to stop bleeding and protect damaged tissue. The HFN7.1 fibronectin antibody is directed against the peptide core and reacts with both the plasma and cellular forms of fibronectin. The antibody blocks the fibronectin-medicated cell attachment not by disrupting the collagen-fibronectin interaction, but by interfering with the attachment of fibronectin to its receptor on the cell surface.á Protein function: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. [The UniProt Consortium]
Keywords: Anti-FN, Anti-FN1, Fibronectin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2124

Properties

Application: FC, IHC, IF
Antibody Type: Monoclonal
Clone: HFN7.1
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Purified human Fibronectin was used as the immunogen for this antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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