Anti-ETBR

Anti-ETBR
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES8504.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES8504.100 100 µl - -

10 - 14 business days*

290.00€
 
The protein encoded by this gene is a G protein-coupled receptor which activates a... more
Product information "Anti-ETBR"
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016], Protein function: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. [The UniProt Consortium] Recommended dilutions: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000. Cellular localization: Cell membrane , Multi-pass membrane protein. internalized after activation by endothelins. .
Keywords: Anti-ET-B, Anti-ETRB, Anti-ET-BR, Anti-Endothelin receptor type B, Anti-Endothelin receptor non-selective type, ETBR rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES8504

Properties

Application: WB, IHC, IF, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse,
Immunogen: Synthesized peptide derived from ETBR at AA range: 31-80
MW: 50 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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