Anti-Estrogen Inducible Protein pS2 (TFF1), clone TFF1/1091

Anti-Estrogen Inducible Protein pS2 (TFF1), clone TFF1/1091
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2880-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V2880-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. It recognizes a polypeptide of... more
Product information "Anti-Estrogen Inducible Protein pS2 (TFF1), clone TFF1/1091"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy. Protein function: Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. [The UniProt Consortium]
Keywords: Anti-BCEI, Anti-TFF1, Anti-hP1.A, Anti-PNR-2, Anti-Protein pS2, Anti-Trefoil factor 1, Anti-Polypeptide P1.A, Anti-Breast cancer estrogen-inducible protein, Estrogen Inducible Protein pS2 Antibody (TFF1)
Supplier: NSJ Bioreagents
Supplier-Nr: V2880-20UG

Properties

Application: FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: TFF1/1091
Conjugate: No
Host: Mouse
Reactivity: Human, Monkey
Immunogen: A peptide from the C-terminus of human TFF1.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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