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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| 600-401-689 | 100 µg | - | - |
3 - 8 business days* |
733.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone... more
Product information "Anti-ESET (SETB, Histone H3-K9 methyltransferase-4, H3-K9-HMTase-4)"
Protein function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation. Probably forms a complex with MBD1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Its activity is dependent on MBD1 and is heritably maintained through DNA replication by being recruited by CAF-1. SETDB1 is targeted to histone H3 by TRIM28/TIF1B, a factor recruited by KRAB zinc-finger proteins. [The UniProt Consortium]
| Keywords: | Anti-ESET, Anti-SETDB1, Anti-KIAA0067, EC=2.1.1.43, Anti-H3-K9-HMTase 4, Anti-SET domain bifurcated 1, Anti-Lysine N-methyltransferase 1E, Anti-Histone H3-K9 methyltransferase 4, Anti-ERG-associated protein with SET domain |
| Supplier: | Rockland Immunochemicals |
| Supplier-Nr: | 600-401-689 |
Properties
| Application: | ELISA, IHC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | synthetic peptide corresponding to amino acids 1058-1075 of human ESET |
| MW: | 170 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K11421 | Matching products |
| UniProt ID : | Q15047 | Matching products |
| Gene ID : | GeneID 9869 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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