28 products were found matching "Q15047"!

Description: SETDB1 Protein, Human, Recombinant is expressed in E. coli with Tag Free. The accession number is Q15047.

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. SETDB1 antibody detects Histone-lysine N-methyltransferase SETDB1, an enzyme responsible for methylating histone H3 at lysine 9 (H3K9), a key epigenetic mark associated with transcriptional repression and heterochromatin formation. Encoded by...

Protein function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby...

Human SetDB1 (variant 2), also known as Histone-lysine Nmethyltransferase SETDB1, SET domain bifurcated 1, KMT1E, ERG-associated protein with SET domain (ESET), GenBank Accession No. NM_012432, a.a. 510- 1290(end) expressed in a Baculovirus Sf9 cell expression system. MW = 114 kDa.

Protein function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby...

In 1X PBS, pH 7.4, with 0.09% sodium azide. The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in...

SETDB1,also named as ESET,KIAA0067 and KMT1E,belongs to the histone-lysine methyltransferase family. It is a SET domain protein with histone H3-K9-specific methyltransferase activity. H3 'Lys-9' trimethylation is coordinated with DNA methylation and represents a specific tag for epigenetic transcriptional repression...

Protein function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby...

Protein function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby...

Protein function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby...

Histone-lysine N-methyltransferase SETDB1 is a member of the SUV39-related protein lysine methyltransferase (PKMT) family and is involved in epigenetic regulation. It is composed of an N-terminal domain that contains two nuclear export signals, two nuclear localization signals, three tudor domains that facilitate...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-397aa. Protein Length: Full Length of Isoform 2. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MSSLPGCIGL DAATATVESE EIAELQQAVV EELGISMEEL RHFIDEELEK MDCVQQRKKQ LAELETWVIQ KESEVAHVDQ LFDDASRAVT NCESLVKDFY SKLGLQYRDS SSEDESSRPT...