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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES19198.50 | 50 µl | - | - |
10 - 14 business days* |
173.00€
|
||
ELK-ES19198.100 | 100 µl | - | - |
10 - 14 business days* |
290.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that... more
Product information "Anti-ERF3B"
Protein function: GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA (PubMed:15987998, PubMed:11524954, PubMed:17562865). GSPT2/ERF3B mediates ETF1/ERF1 delivery to stop codons: The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site (PubMed:15987998). GTP hydrolysis by GSPT2/ERF3B induces a conformational change that leads to its dissociation, permitting ETF1/ERF1 to accommodate fully in the A-site (PubMed:15987998). Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (PubMed:19417104). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm .
Keywords: | Anti-ERF3B, Anti-eRF3b, Anti-GSPT2, Anti-G1 to S phase transition protein 2 homolog, Anti-Eukaryotic peptide chain release factor subunit 3b, Anti-Eukaryotic peptide chain release factor GTP-binding subunit ERF3B, ERF3B rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES19198 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from human ERF3B AA range: 182-232 |
Format: | Purified |
Database Information
KEGG ID : | K03267 | Matching products |
UniProt ID : | Q8IYD1 | Matching products |
Gene ID : | GeneID 23708 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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