Anti-ERF3B

Anti-ERF3B
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES19198.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES19198.100 100 µl - -

10 - 14 business days*

290.00€
 
Protein function: GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that... more
Product information "Anti-ERF3B"
Protein function: GTPase component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons UAA, UAG and UGA (PubMed:15987998, PubMed:11524954, PubMed:17562865). GSPT2/ERF3B mediates ETF1/ERF1 delivery to stop codons: The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site (PubMed:15987998). GTP hydrolysis by GSPT2/ERF3B induces a conformational change that leads to its dissociation, permitting ETF1/ERF1 to accommodate fully in the A-site (PubMed:15987998). Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (PubMed:19417104). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm .
Keywords: Anti-ERF3B, Anti-eRF3b, Anti-GSPT2, Anti-G1 to S phase transition protein 2 homolog, Anti-Eukaryotic peptide chain release factor subunit 3b, Anti-Eukaryotic peptide chain release factor GTP-binding subunit ERF3B, ERF3B rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES19198

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthesized peptide derived from human ERF3B AA range: 182-232
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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