Anti-EPRS

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-959A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A303-959A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A303-959A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in... more
Product information "Anti-EPRS"
Protein function: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA (PubMed:1756734, PubMed:24100331, PubMed:23263184). Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript- selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. [The UniProt Consortium]
Keywords: Anti-EPRS, Anti-GLNS, Anti-GluRS, Anti-PIG32, EC=6.1.1.17, Anti-Proline--tRNA ligase, Anti-Prolyl-tRNA synthetase, Anti-Glutamate--tRNA ligase, Anti-Glutamyl-tRNA synthetase, Anti-Glutamatyl-prolyl-tRNA synthetase
Supplier: Bethyl Laboratories
Supplier-Nr: A303-959A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, Small-eared Galago)
Immunogen: synthetic peptide. The epitope recognized by A303-959A-T maps to a region between residue 950 to 1000 of human Glutamyl-prolyl-tRNA Synthetase using the numbering given in entry NP_004437.2 (GeneID 2058).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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