Anti-EPAC1

Anti-EPAC1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-BB1 100 µg - -

6 - 10 business days*

848.00€
 
Anti-EPAC1 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-EPAC1"
Anti-EPAC1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of EPAC1 are known to exist, this antibody will detect both isoforms. EPAC1 antibody is predicted to not cross-react with EPAC2. Protein function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho- mediated signaling. Required for the actin rearrangement at cell- cell junctions, such as stress fibers and junctional actin. [The UniProt Consortium]
Keywords: Anti-CGEF1, Anti-EPAC 1, Anti-RAPGEF3, Anti-cAMP-GEFI, Anti-Rap guanine nucleotide exchange factor 3, Anti-Exchange factor directly activated by cAMP 1, Anti-Exchange protein directly activated by cAMP 1, Anti-cAMP-regulated guanine nucleotide exchange fa
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-BB1

Properties

Application: ELISA, IHC, IFM, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: 18 amino acid synthetic peptide near the N-terminus of human EPAC1.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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