Anti-ELL2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-505A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A302-505A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Elongation factor component of the super elongation complex (SEC), a complex... more

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Product information "Anti-ELL2"

Protein function: Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane- specific to secretory IgH mRNA expression. [The UniProt Consortium]

Keywords:	Anti-ELL2, Anti-RNA polymerase II elongation factor ELL2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-505A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rat, X. laevis, X. tropicalis, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, duckbill platypus, white-tufted-ear marmoset, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-505A-T maps to a region between residue 400 and 450 of human elongation factor, RNA polymerase II, 2 using the numbering given in entry NP_036213.2 (GeneID 22936).
Format:	Antigen Affinity Purified