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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA060259.25 | 25 µl | - |
7 - 10 business days* |
300.00€
|
|||
| ATA-HPA060259.100 | 100 µl | - |
7 - 10 business days* |
421.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of... more
Product information "Anti-EHMT2"
Protein function: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. May also methylate histone H1. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Also methylates CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6, KLF12 and itself. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 85% and to rat: 87%
| Keywords: | Anti-BAT8, Anti-EHMT2, Anti-Protein G9a, Anti-H3-K9-HMTase 3, Anti-HLA-B-associated transcript 8, Anti-Lysine N-methyltransferase 1C, Anti-Histone H3-K9 methyltransferase 3, Anti-Histone-lysine N-methyltransferase EHMT2 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA060259 |
Properties
| Application: | ICC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PRSEETLPKA TPDSLEPAGP SSPASVTVTV GDEGADTPVG ATPLIGDESE NLEGDGDLRG GRILLGHATK SFPSS (ATA-APrEST89903) |
Database Information
| KEGG ID : | K11420 | Matching products |
| UniProt ID : | Q96KQ7 | Matching products |
| Gene ID | GeneID 10919 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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