Anti-EHMT1

Anti-EHMT1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA060022.25 25 µl -

7 - 10 business days*

300.00€
ATA-HPA060022.100 100 µl -

7 - 10 business days*

421.00€
 
Protein function: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of... more
Product information "Anti-EHMT1"
Protein function: Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 72% and to rat: 74%
Keywords: Anti-GLP, Anti-GLP1, Anti-EHMT1, Anti-EUHMTASE1, Anti-Eu-HMTase1, Anti-H3-K9-HMTase 5, Anti-G9a-like protein 1, Anti-Lysine N-methyltransferase 1D, Anti-Histone H3-K9 methyltransferase 5, Anti-Histone-lysine N-methyltransferase EHMT1
Supplier: Atlas Antibodies
Supplier-Nr: HPA060022

Properties

Application: ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ADGETNGSCE NSDASSHANA AKHTQDSARV NPQDGTNTLT RIAENGVSER DSEAAKQNHV TADDFVQTSV IGSNGYILNK PALQAQPLRT TSTLASSLPG HAAKTLPGGA GKGRTPSAFP QTPAAPPATL (ATA-APrEST89895)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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