Anti-EGFR (L858R), monoclonal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NB-26082	100 µl		-	-	3 - 16 business days*		717.00€

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Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50%... more

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Product information "Anti-EGFR (L858R), monoclonal"

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. Defects in EGFR are associated with lung cancer (LNCR).

Keywords:	Anti-EGFR, Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase erbB-1
Supplier:	NewEast Biosciences
Supplier-Nr:	26082

Properties

Application:	ELISA, WB, IF, IHC
Antibody Type:	Monoclonal
Conjugate:	No
Host:	Mouse
Species reactivity:	vertebrates
Immunogen:	synthetic peptide from the internal region of EGFR which includes the mutation of L858R, human origin
Format:	Purified