972 products were found matching "K04361"!
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Erlotinib
Item number: Cay10483-250
Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR...
| Keywords: | NSC 718781, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine |
| Application: | Tyrosine kinase inhibitor |
| CAS | 183321-74-6 |
| MW: | 393.4 D |
From 51.00€
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Anti-EGFR-Anti-c-Met Bispecific Antibody (Amivantamab)
Item number: BPS-102870-1
Anti-EGFR-Anti-c-Met Bispecific Antibody is a purified recombinant human bispecific antibody targeting EGFR (epidermal growth factor receptor) and c-Met. It is also known as Amivantamab, and being studied for the treatment of patients with NSCLC (non-small cell lung cancer) that have EGFR exon 20 mutations. EGFR...
| Keywords: | EGFR, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
| Application: | Binding assays |
| Host: | Human |
| Species reactivity: | human |
From 506.00€
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Human EGFR (Epidermal Growth Factor Receptor) Microsample...
Item number: ELK-ELK2110MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human EGFR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human EGFR. Next,...
| Keywords: | EGFR, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1 |
| Application: | ELISA |
| Species reactivity: | human |
From 374.00€
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Mouse EGFR (Epidermal Growth Factor Receptor) Microsample...
Item number: ELK-ELK2421MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse EGFR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse EGFR. Next,...
| Keywords: | Egfr, Epidermal growth factor receptor |
| Application: | ELISA |
| Species reactivity: | mouse |
From 374.00€
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Anti-EGFR, monoclonal
Item number: ELK-EM1044.100
The epidermal growth factor receptor (EGFR, ErbB-1, HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and...
| Keywords: | Anti-EGFR, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
| Application: | WB, IHC, IF |
| Host: | Mouse |
| Species reactivity: | human |
From 173.00€
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Anti-EGFR, monoclonal
Item number: ELK-EM1134.100
The epidermal growth factor receptor (EGFR, ErbB-1, HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and...
| Keywords: | Anti-EGFR, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
| Application: | WB, IHC, IF, IP |
| Host: | Mouse |
| Species reactivity: | human |
From 173.00€
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EGFR (D770-N771insG), GST-Tag Recombinant
Item number: BPS-84154-1
Recombinant human EGFR (epidermal growth factor receptor), encompassing amino acids 668-end. This construct contains a D770-N771isnG, and N-terminal GST-tag. This protein was affinity purified. EGFR (epidermal growth factor receptor), also known as ERBB-1 and HER1, is the cell-surface tyrosine kinase receptor for...
| Keywords: | EGFR, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
| Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Expressed in: | Insect cells |
| Origin: | human |
| MW: | 89 kD |
From 1,007.00€
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EGFR (D770-N771insNPG, T790M), GST-Tag Recombinant
Item number: BPS-84155-1
Recombinant human EGFR (epidermal growth factor receptor), encompassing amino acids 668-end. This construct contains a D770-N771isnNPG, the mutation T790M and N-terminal GST-tag. This protein was affinity purified. EGFR (epidermal growth factor receptor), also known as ERBB-1 and HER1, is the cell-surface tyrosine...
| Keywords: | EGFR, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
| Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Expressed in: | Insect cells |
| Origin: | human |
| MW: | 89 kD |
From 1,007.00€
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EGFR (V769-D770insASV), GST-Tag Recombinant
Item number: BPS-84156-1
Recombinant human EGFR (epidermal growth factor receptor), encompassing amino acids 665-end. This construct contains V769-D770insASV, and N-terminal GST-tag. This protein was affinity purified. Note: No significant kinase activity was detected with this protein. EGFR (epidermal growth factor receptor), also known as...
| Keywords: | EGFR, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 |
| Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Expressed in: | Insect cells |
| Origin: | human |
| MW: | 90 kD |
From 1,007.00€
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Anti-EGF Receptor / EGFR, clone 688CT33.1.3
Item number: NSJ-F40405-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding...
| Keywords: | Anti-EGFR, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
| Application: | WB, IHC, ELISA |
| Host: | Mouse |
| Species reactivity: | human |
From 361.00€
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Anti-EGF Receptor / EGFR
Item number: NSJ-F50597-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely...
| Keywords: | Anti-EGFR, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
| Application: | IHC, WB, ELISA |
| Host: | Rabbit |
| Species reactivity: | human |
From 361.00€
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Anti-EGF Receptor / EGFR, clone 51CT78.40.5
Item number: NSJ-F40415-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding...
| Keywords: | Anti-EGFR, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor tyrosine-protein kinase... |
| Application: | IHC, FC, WB, ELISA |
| Host: | Mouse |
| Species reactivity: | human |
From 361.00€
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