Protein function: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. [The UniProt Consortium]
synthetic peptide. The epitope recognized by A301-687A-T maps to a region between residue 675 and 725 of human calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase using the numbering given in entry NP_037434.1 (GeneID 29904).