Anti-EED

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA061140.25	25 µl		-		7 - 10 business days*		320.00€
ATA-HPA061140.100	100 µl		-		7 - 10 business days*		450.00€

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Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which... more

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Product information "Anti-EED"

Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED- EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-hEED, Anti-WAIT-1, Anti-Polycomb protein EED, Anti-Embryonic ectoderm development protein, Anti-WD protein associating with integrin cytoplasmic tails 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA061140

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: HPLLAVAGSR GIIRIINPIT MQCIKHYVGH GNAINELKFH PRDPNLLLSV SKDHALRLWN IQTDTLVAIF GGVEGHRDEV LSADYDLLGE KIMSCGMDHS LK (ATA-APrEST87903)